Study record managers: refer to the Data Element Definitions if submitting registration or results information. The aim: The evaluation of the influence of a probiotics therapy on mood improvement and the reduction of depressive symptoms in women in the perimenopausal age group. The study hypothesis: By using periodic probiotics therapy it is possible to positively influence the mood of women with depressive syndromes. These efforts focus on the improvement of the functioning of the gut barrier and gut-brain axis. In practice, such activities should lead to the reduction in the dysfunction of the barrier, the reduction of endotoxemia and the concentration of neurotoxic metabolites of tryptophan in blood with the simultaneous increase in the content of butyric acid that has a neuroprotective effect. The of the trial: intervention, cohort, randomized, double-blind, using placebo. Currently, there is an urgent problem to develop recommendations regarding the nutrition and probiotics therapy that could complement the therapy of women with mood disorders.
Less than 20 years in patients with an EDSS score at screening 7. Latest version submitted February 17, on ClinicalTrials. A study version is represented by a row in the table.
Synonyms for arranged marriage include marriage of convenience, arranged match, mariage blanc, mariage de convenance, matchmaking, blind date and matching. Usage of marriage Arranged marriage is a highly controversial subject in the world today because of the idea of free will and the modern society, as well as the relatively modern concept of love. One does not know what to expect out of the marriage, one is in minimal control of the relationship, and one is battling loads of family interference. Arranged Marriage.
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