New metastatic breast cancer treatments

About video
A core needle biopsy uses a long, hollow tube to extract a sample of tissue. Here, a biopsy of a suspicious breast lump is being done. The sample is sent to a laboratory for testing. During a breast MRI , you lie on your stomach on a padded scanning table.
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U.S. Food and Drug Administration

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Recommended Treatments for Metastatic Breast Cancer

The EASI system delivers ImmunoBait particles into the cells that line the lungs' blood vessels, where they release their chemokine payload. This action stimulates the body's immune system to produce the chemokine on its own, and creates an immune response against lung metastases. Date November 16, When a patient with cancer is told the devastating news that their disease has spread, or metastasized, to a new part of their body, it has most often moved to their lungs. There are no treatments approved for lung metastasis, which is the leading cause of death from metastatic disease. Rather than viewing lung metastasis as unfortunate fallout from a primary tumor elsewhere, the team focused on treating the metastasis itself by delivering immune-cell-attracting chemicals into lung cancers via red blood cells. Not only did this approach halt lung tumor growth in mice with metastatic breast cancer, it also acted as a vaccine and protected the animals against future cancer recurrences.
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For Metastatic HER2-Positive Breast Cancer, New Treatments Emerge

The drug Verzenio abemaciclib when added to hormonal therapy can significantly reduce the risk of breast cancer recurrence in women with a form of early-stage but high-risk breast cancer known as HR-positive, HER2-negative breast cancer, according to data presented September 19 at the European Society for Medical Oncology ESMO Virtual Congress. Hormone receptor positive HR-positive breast cancer is the most common type of breast cancer. Many patients with early-stage disease are cured using a range of treatments, including surgery, radiation, chemotherapy, and hormone treatment.
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January 8, , by NCI Staff. The drug is approved for use in combination with trastuzumab Herceptin and capecitabine Xeloda by patients whose cancer cannot be removed surgically or has spread to other parts of the body metastasized and who have undergone at least one prior line of treatment. Two new treatment options are emerging for women with metastatic breast cancer, following positive results from clinical trials. The trials tested the drugs tucatinib and trastuzumab deruxtecan Enhertu in women who had been previously treated for metastatic breast cancer that overproduces the HER2 protein, known as HER2-positive breast cancer.
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